Gremio are still searching for their first win in this season s Copa Libertadores after going down to Universidad Catolica, while Libertad made it three victories from three matches.
Brazilian side Gremio only have one point from three Group H fixtures following Thursday s 1-0 loss away to Catolica – the club s second consecutive defeat in the competition.
After their loss at home to Libertad on matchday two, three-time Libertadores winners Gremio – the 2017 champions – succumbed to Sebastian Saez s 17th-minute goal in Santiago, Chile.
Stefano Magnasco s cross found Argentine forward Saez, who side-footed a volley past Paulo Victor for the Chilean hosts.
Full Time! take all three points against thanks to an early goal!
— CONMEBOL Libertadores (@TheLibertadores)
Catolica improved to six points, five ahead of third-placed Gremio and three adrift of leaders Libertad.
Paraguayan outfit Libertad preserved their 100 per cent record after accounting for lowly 10-man Rosario Central 2-0.
Second-half goals from Matias Espinoza and Jorge Recalde lifted Libertad as Rosario played out the remaining 15 minutes with 10 men following Marcelo Ortiz s second yellow card.
Meanwhile, Olimpia scored three goals in the second half to blitz hosts Sporting Cristal 3-0 in Group C.